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Microsatellite Variability, Methylation & Cancer

The overall goal of this study is to investigate the hypothesis that the genes in the molecular pathway(s) of cancer progression are subject to transcriptional regulation by microsatellite repeat sequence variability...

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Molecular Pathology of Deafness

Deafness is an important and common cause of human morbidity.  It is estimated that 1/1000 individuals before 3 years of age years are deaf, of which 35-50% are thought to be inherited.  We have studied members of a large Central Illinois family with autosomal dominant Charcot-Marie-Tooth disease (CMT) associated with profound and progressive sensorineural deafness...

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Effects of E-cigarette Exposure on Lung Cells

This research focuses on the analysis of the components of e-cigarette filling solutions and their implications for biological systems.  E-cigarettes are increasingly reported to cause adverse health effects and therefore may pose a significant public health risk....

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